Separations of biogenic amines in Drosophila
Small-scale separations are under development for cellular and subcellular analysis. Capillary electrophoresis with electrochemical, fluorescence, and mass spectrometric detection has been used to monitor catecholamines, amino acids, peptides, and proteins in single cells. In addition, we have developed dynamic electrophoresis techniques that permit continuous separations from ultrasmall biological environments with a large effort in understanding the function of biogenic amines in the brain of the fruit fly Drosophila melanogaster in collaboration with Kyung-An Han's group in the Penn State Biology Department.
